ZO Skin Health Firming Serum

ZO Skin Health Firming Serum is an anti-aging breakthrough in skin structure and shape. This mild, lightweight, and tolerable formulation is indicated for all skin types — including sensitive skin areas — to reinforce skin health, hydrate deeply, and support visible improvement in skin elasticity and firmness. Combining the proprietary ZCORE™ complex, sodium DNA, and ZO-RRS2® plant stem cell complex, Firming Serum visibly tightens and firms the skin, improves the appearance of sagging and skin laxity, and helps define facial contours with consistent twice-daily use.

Clinically evaluated in a 24-week independent third-party study, Firming Serum delivers measurable improvements in skin firmness, elasticity, and contour definition. Available in two sizes — 28ml and 47ml — it is suitable for use morning and evening on the face and sensitive skin areas as part of a complete ZO® Skin Health anti-aging regimen.

Skin Types

Suitable for all skin types including sensitive skin. Its mild, lightweight formulation is well-tolerated across dry, normal, oily, combination, and sensitive skin types seeking visible improvement in firmness, elasticity, and facial contour definition.

Skin Concerns

Formulated to address visible signs of skin aging including loss of firmness and elasticity, sagging and skin laxity, loss of facial contour definition, and free radical-induced skin damage. Ideal for those seeking a daily anti-aging serum that delivers structural improvement in skin shape and firmness alongside antioxidant protection.

Benefits

• Visibly tightens and firms the skin with continued twice-daily use
• Improves the appearance of sagging and skin laxity
• Helps define and restore facial contours
• Supports the appearance of healthy skin and the skin’s natural renewal process
• Defends against free radical damage with the ZO-RRS2® antioxidant complex
• Mild, lightweight, and tolerable — suitable for all skin types including sensitive
• Available in 28ml and 47ml sizes

Key Ingredients

• ZCORE™ Complex — ZO®’s proprietary firming complex that helps improve the appearance of visibly sagging skin by targeting the structural components of the skin responsible for firmness and elasticity. ZCORE™ works to reinforce the skin’s internal support network, delivering progressive improvement in skin laxity and contour definition with consistent daily use.
• Sodium DNA — A bioactive ingredient that supports the appearance of a more visibly defined facial contour by promoting skin health and cellular renewal. Sodium DNA helps reinforce the skin’s natural repair mechanisms and supports the structural integrity of the skin, contributing to the formula’s overall firming and contouring efficacy.
• ZO-RRS2® (Plant Stem Cell Complex) — ZO®’s exclusive plant stem cell complex that provides powerful antioxidant protection against free radical damage from environmental aggressors. Its antioxidant action helps defend the skin against the oxidative stress that accelerates the breakdown of collagen and elastin — the structural proteins responsible for skin firmness and elasticity — supporting the long-term maintenance of the formula’s firming results.

Clinical Evidence

Firming Serum was evaluated in a 24-week independent third-party clinical study of 45 subjects — females aged 40–69 across Fitzpatrick skin types II–IV — to assess its efficacy in improving the appearance of skin firmness, elasticity, and facial contour definition. The study was conducted with concurrent use of ZO® Gentle Cleanser and Sunscreen + Primer Broad-Spectrum SPF 30, with assessments conducted at 12 and 24 weeks. Results demonstrated clinically meaningful improvements in skin firmness, laxity, and contour definition over the study period.

How to Use

Apply Firming Serum to clean, dry skin each morning and evening. Allow to absorb fully before applying moisturizer and sunscreen. For best results, use consistently twice daily as part of a complete ZO® Skin Health anti-aging regimen.