ZO Skin Health Pigment Control Crème

ZO Skin Health Pigment Control Crème is a prescription-strength pigment-correcting treatment formulated with 2% hydroquinone and glycolic acid to correct pigmentation disorders, promote a more even skin tone, and mitigate pigment-forming irritations. By combining the gold-standard depigmenting agent hydroquinone with the exfoliating and cell-turnover-accelerating action of glycolic acid, this crème addresses the full cycle of hyperpigmentation — inhibiting melanin production at the source while simultaneously accelerating the removal of existing pigmented skin cells to reveal a clearer, more even complexion.

Formulated for use under the guidance of a skincare professional, Pigment Control Crème is indicated for the treatment of melasma, post-inflammatory hyperpigmentation (PIH), sun-induced discoloration, and other pigmentation disorders. It is a targeted treatment step within a complete ZO® Skin Health pigment-correction regimen and should be used in conjunction with a broad-spectrum sunscreen to prevent re-pigmentation.

Skin Types

Suitable for skin types experiencing hyperpigmentation, melasma, post-inflammatory hyperpigmentation, or sun-induced discoloration. For use under the guidance of a physician or skincare professional. Not recommended for use during pregnancy or breastfeeding without medical supervision.

Skin Concerns

Formulated to address hyperpigmentation, melasma, post-inflammatory hyperpigmentation (PIH), sun-induced discoloration, uneven skin tone, and pigment-forming irritations. Ideal for those seeking a clinically effective, prescription-strength pigment-correcting treatment that addresses both the cause and the visible appearance of skin discoloration.

Benefits

• Lessens the appearance of discoloration for a more even, uniform skin tone
• 2% hydroquinone inhibits melanin production to correct pigmentation disorders at the source
• Glycolic acid accelerates cell turnover to remove existing pigmented skin cells and reveal clearer skin
• Mitigates pigment-forming irritations that trigger or worsen hyperpigmentation
• Promotes a progressively more even skin tone with consistent use
• Prescription-strength formula for clinically meaningful pigment correction

Key Ingredients

• 2% Hydroquinone — The gold-standard depigmenting agent in dermatology, hydroquinone works by inhibiting tyrosinase — the key enzyme responsible for melanin synthesis — thereby reducing the production of new pigment at the source. At 2%, hydroquinone is the highest concentration available without a prescription in Canada and is clinically proven to effectively reduce the appearance of melasma, post-inflammatory hyperpigmentation, and sun-induced discoloration with consistent use under professional guidance.
• Glycolic Acid — An alpha-hydroxy acid (AHA) that accelerates the skin’s natural cell turnover by dissolving the bonds between dead, pigmented skin cells at the surface — speeding their removal and revealing fresher, more evenly toned skin beneath. Working synergistically with hydroquinone, glycolic acid enhances the penetration and efficacy of the depigmenting active while simultaneously improving skin texture and radiance.

How to Use

Apply Pigment Control Crème to affected areas as directed by your physician or skincare professional. Use consistently as part of a complete ZO® Skin Health pigment-correction regimen. Always apply a broad-spectrum sunscreen with SPF 30 or higher every morning when using this product — sun exposure will trigger re-pigmentation and undermine treatment results.

This product contains 2% hydroquinone. Use only as directed by a physician or skincare professional. Avoid contact with eyes. If irritation or sensitivity develops, discontinue use and consult your healthcare provider. Not recommended during pregnancy or breastfeeding without medical supervision.

Warning: This product contains alpha hydroxy acids (AHAs) that may increase your skin’s sensitivity to the sun and the possibility of sunburn. Use a broad-spectrum sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterward.