Acne Complex

ZO Skin Health's Acne Complex is a revolutionary 360° topical treatment that targets every stage of blemish formation — from active breakouts to the lingering marks and textural scarring left behind. Clinically proven to reduce blemish severity, prevent future breakouts, and visibly improve post-blemish red and brown marks, this creamy treatment serum is a comprehensive solution for oily and blemish-prone skin. Fragrance-free and fast-absorbing, it delivers powerful results without compromising skin comfort.

50 mL / 1.7 Fl. Oz.

Benefits

• Clears all grades of blemishes — from blackheads to cystic acne
• Helps to prevent future blemishes by keeping pores clear
• Minimizes the appearance of post-blemish red and brown marks
• Improves the look of textural blemish scarring for visibly smoother skin
• Creamy treatment serum absorbs quickly without heaviness
• Fragrance-free formula suitable for sensitive, blemish-prone skin

Key Ingredients

• 1% Retinol in a Microemulsion — Promotes healthy cell turnover and exfoliation within pores to prevent future acne formation and improve the look of textural scarring over time.
• 2% Encapsulated Salicylic Acid — Unclogs impactions and clears existing breakouts using an advanced delivery system that provides extended, sustained pore-clearing action.
• Potassium Azeloyl Diglycinate + Cetyl Tranexamate Mesylate — Azelaic acid and tranexamic acid derivatives that work together to minimize the formation of post-acne red and brown marks, promoting a clear and even skin tone.
• ZO-RRS²® — An exclusive plant stem cell complex that soothes visible redness while helping to neutralize aging free radicals for calmer, healthier-looking skin.

Skin Type

Formulated specifically for oily and blemish-prone skin. Suitable for use under physician supervision for all skin types experiencing acne concerns.

Directions For Use

Due to the unique potency of Acne Complex, begin use gradually to allow skin to acclimate to the active ingredients.

• After completing your Getting Skin Ready® routine, apply a thin layer 2–3 times per week.
• Gradually increase to daily use as tolerated by your skin.
• Pair with ZO's Hydrating Crème to soothe and comfort skin during the acclimation period.
• Wear a broad-spectrum sunscreen SPF 30 or higher daily, especially during initial retinol acclimation.
• Provider monitoring is recommended for best results.
• Suitable for both AM and PM use.

Anticipated Reactions

Redness, flakiness, dryness, burning, or stinging are all normal and anticipated reactions when beginning retinol use. With regular product use, skin will acclimate, revealing a smoother, more even-toned, and youthful-looking complexion. Pair your retinol with a ZO® functional hydrator to minimize these reactions. Consult a physician for a customized retinol protocol. Like prescription retinoic acid, retinol will make your skin more sensitive to the sun — wear SPF 30 or higher daily without exception.